Next Generation Sequencing (NGS)

Next‑Generation Sequencing (NGS) is a high‑throughput molecular technology used for comprehensive virus characterization and genetic analysis in vaccine development and immunogenicity studies. VisMederi NGS services span from full‑genome and targeted sequencing for virus identification, strain typing and confirmation of genetic identity, as well as detailed assessment of minority variant populations. The approach supports monitoring of antigenic regions relevant to immune recognition, evaluation of antigenic drift or emergence of escape variants and comparability of seed lots. NGS is also applied for sensitive detection of adventitious viruses, mixed viral populations, and microbial contaminants. When implemented within an appropriate quality framework, NGS provides high‑resolution genetic insight supporting viral characterization, process development, and regulatory submissions across clinical and non‑clinical vaccine programs.