Collaborative studies
Therapeutic inhibition of telomeric DNA damage response rescues hematopoietic dysfunction driven by telomere shortening and aging.
Oppezzo A, Sepe S, Cicio G, Cancila V, Sasso E, Conti A, Marinelli E, Cabrini M, Pallavi R, Iacomino N, Simoni M, Malyshev D, Boggio S, Di Lillo A, Rosso I, Tavella S, Trastus LA, Rossiello F, Roscia G, Cantaloni P, Manenti A, Cavalcante P, Pelicci PG, Di Micco R, Nicosia A, Tripodo C, d’Adda di Fagagna F. Nat Aging. 2026;6(7):1377–1394. doi: 10.1038/s43587-026-01136-9.
Development of an intranasal, universal influenza vaccine in an EU-funded public-private partnership: the FLUniversal consortium.
Cnossen VM, Moreira PCL, Engelhardt OG, Samolej J, Groeneveld GH, Jochems SP, Huisman W, Pedersen GK, Wørzner K, Recek L, Piccini G, Trombetta CM, Aspelund A, Hoag A, Reiter M, Wick C, Muster T, Kamerling IMC. Front Immunol. 2025 May 23;16:1568778. doi: 10.3389/fimmu.2025.1568778. PMID: 40486504. PMCID: PMC12141322.
Standardised quantitative assays for anti-SARS-CoV-2 immune response used in vaccine clinical trials by the CEPI Centralized Laboratory Network: a qualification analysis.
Manak M, Gagnon L, Phay-Tran S, Levesque-Damphousse P, Fabie A, Daugan M, Khan ST, Proud P, Hussey B, Knott D, Charlton S, Hallis B, Medigeshi GK, Garg N, Anantharaj A, Raqib R, Sarker P, Alam MM, Rahman M, Murreddu M, Balgobind A, Hofman R, Grappi S, Coluccio R, Calandro P, Montomoli E, Mattiuzzo G, Prior S, Le Duff Y, Page M, Mitchell J, Schwartz LM, Bartsch YC, Azizi A; CEPI CLN Study Group. Lancet Microbe. 2024 Jan 23;S2666-5247(23)00324-5. doi: 10.1016/S2666-5247(23)00324-5. PMID: 38278167.
Development of a composite scoring system to rank communities at high risk of zero-dose children in Cameroon: A geospatial analysis.
Saidu Y, Agbor VN, Di Mattei P, Nchinjoh SC, Edwidge NN, Njoh AA, Muteh NJ, Prescott M, Wiwa O, Diack D, Flegere J, Montomoli E, Costa Clemens SA, Clemens R. J Glob Health. 2023 Nov 17;13:04136. doi: 10.7189/jogh.13.04136. PMID: 37971948.
The faces behind vaccination: unpacking the attitudes, knowledge, and practices of staff of Cameroon’s Expanded Program on Immunization.
Saidu Y, Gu J, Ngenge BM, Nchinjoh SC, Adidja A, Nnang NE, Muteh NJ, Zambou VM, Mbanga CM, Agbor VN, Ousmane D, Njoh AA, Flegere J, Diack D, Wiwa O, Montomoli E, Clemens SAC, Clemens R. Hum Resour Health. 2023 Nov 13;21(1):88. doi: 10.1186/s12960-023-00869-7. PMID: 37957695.
Regional and sex inequalities of avoidable mortality in Italy: A time trend analysis.
Golinelli D, Guarducci G, Sanna A, Lenzi J, Sanmarchi F, Fantini MP, Montomoli E, Nante N. Public Health Pract (Oxf). 2023 Oct 26;6:100449. doi: 10.1016/j.puhip.2023.100449. eCollection 2023 Dec. PMID: 38028252.
Assessment of immunization data management practices in Cameroon: unveiling potential barriers to immunization data quality.
Saidu Y, Gu J, Ngenge BM, Nchinjoh SC, Adidja A, Nnang NE, Muteh NJ, Zambou VM, Mbanga C, Agbor VN, Ousmane D, Njoh AA, Flegere J, Diack D, Wiwa O, Montomoli E, Clemens SAC, Clemens R. BMC Health Serv Res. 2023 Sep 27;23(1):1033. doi: 10.1186/s12913-023-09965-9. PMID: 37759205.
Human Papillomavirus Epidemiology and Prevention: Is There Still a Gender Gap?
Milano G, Guarducci G, Nante N, Montomoli E, Manini I. Vaccines (Basel). 2023 Jun 4;11(6):1060. doi: 10.3390/vaccines11061060. PMID: 37376449.
Haemagglutination inhibition and virus microneutralisation serology assays: use of harmonised protocols and biological standards in seasonal influenza serology testing and their impact on inter-laboratory variation and assay correlation: A FLUCOP collaborative study.
Waldock J, Remarque EJ, Zheng L, Ho S, Hoschler K, Neumann B, Sediri-Schön H, Trombetta CM, Montomoli E, Marchi S, Lapini G, Zhou F, Lartey SL, Cox RJ, Facchini M, Castrucci MR, Friel D, Ollinger T, Caillet C, Music N, Palladino G, Engelhardt OG; FLUCOP consortium. Front Immunol. 2023 Apr 18;14:1155552. doi: 10.3389/fimmu.2023.1155552. eCollection 2023. PMID: 37143658.
The Hidden Impact of the COVID-19 Pandemic on Routine Childhood Immunization Coverage in Cameroon.
Saidu Y, Di Mattei P, Nchinjoh SC, Edwige NN, Nsah B, Muteh NJ, Ndoula ST, Abdullahi R, Zamir CS, Njoh AA, Adidja A, Ndiaye S, Wiwa O, Montomoli E, Clemens SAC. Vaccines (Basel). 2023 Mar 14;11(3):645. doi: 10.3390/vaccines11030645. PMID: 36992229.
An external quality assessment feasibility study; cross laboratory comparison of haemagglutination inhibition assay and microneutralization assay performance for seasonal influenza serology testing: A FLUCOP study.
Waldock J, Weiss CD, Wang W, Levine MZ, Jefferson SN, Ho S, Hoschler K, Londt BZ, Masat E, Carolan L, Sánchez-Ovando S, Fox A, Watanabe S, Akimoto M, Sato A, Kishida N, Buys A, Maake L, Fourie C, Caillet C, Raynaud S, Webby RJ, DeBeauchamp J, Cox RJ, Lartey SL, Trombetta CM, Marchi S, Montomoli E, Sanz-Muñoz I, Eiros JM, Sánchez-Martínez J, Duijsings D, Engelhardt OG. Front Immunol. 2023 Feb 28;14:1129765. doi: 10.3389/fimmu.2023.1129765. eCollection 2023. PMID: 36926342.
Harmonization and qualification of intracellular cytokine staining to measure influenza-specific CD4+ T cell immunity within the FLUCOP consortium.
Begue S, Waerlop G, Salaun B, Janssens M, Bellamy D, Cox RJ, Davies R, Gianchecchi E, Medaglini D, Montomoli E, Pettini E, Leroux-Roels G, Clement F, Pagnon A. Front Immunol. 2022 Oct 20;13:982887. doi: 10.3389/fimmu.2022.982887. eCollection 2022. PMID: 36341380.
Harmonization and qualification of an IFN-γ Enzyme-Linked ImmunoSpot assay (ELISPOT) to measure influenza-specific cell-mediated immunity within the FLUCOP consortium.
Waerlop G, Leroux-Roels G, Lambe T, Bellamy D, Medaglini D, Pettini E, Cox RJ, Trieu MC, Davies R, Bredholt G, Montomoli E, Gianchecchi E, Clement F. Front Immunol. 2022 Sep 8;13:984642. doi: 10.3389/fimmu.2022.984642. eCollection 2022. PMID: 36159843.
Validation of a Harmonized Enzyme-Linked-Lectin-Assay (ELLA-NI) Based Neuraminidase Inhibition Assay Standard Operating Procedure (SOP) for Quantification of N1 Influenza Antibodies and the Use of a Calibrator to Improve the Reproducibility of the ELLA-NI With Reverse Genetics Viral and Recombinant Neuraminidase Antigens: A FLUCOP Collaborative Study.
Bernard MC, Waldock J, Commandeur S, Strauß L, Trombetta CM, Marchi S, Zhou F, van de Witte S, van Amsterdam P, Ho S, Hoschler K, Lugovtsev V, Weir JP, Montomoli E, Cox RJ, Engelhardt OG, Friel D, Wagner R, Ollinger T, Germain S, Sediri-Schön H. Front Immunol. 2022 Jun 17;13:909297. doi: 10.3389/fimmu.2022.909297. eCollection 2022. PMID: 35784305.
Immunity to measles in Italian children and adolescents: a persistent problem in view of measles elimination.
Marchi S, Monti M, Viviani S, Remarque EJ, Esposito S, Principi N, Ruggiero L, Montomoli E, Trombetta CM. J Public Health (Oxf). 2021 Dec 10;43(4):e601-e609. doi: 10.1093/pubmed/fdaa153. PMID: 32915205.
System-oriented optimization of multi-target 2,6-diaminopurine derivatives: Easily accessible broad-spectrum antivirals active against flaviviruses, influenza virus and SARS-CoV-2.
Vicenti I, Martina MG, Boccuto A, De Angelis M, Giavarini G, Dragoni F, Marchi S, Trombetta CM, Crespan E, Maga G, Eydoux C, Decroly E, Montomoli E, Nencioni L, Zazzi M, Radi M. Eur J Med Chem. 2021 Nov 15;224:113683. doi: 10.1016/j.ejmech.2021.113683. Epub 2021 Jul 5. PMID: 34273661.
Discovery of the First-in-Class DDX3X Fluorescent Inhibitor.
Brai A, Boccuto A, Monti M, Marchi S, Vicenti I, Saladini F, Trivisani CI, Pollutri A, Trombetta CM, Montomoli E, Riva V, Garbelli A, Nola EM, Zazzi M, Maga G, Dreassi E, Botta M. ACS Med Chem Lett. 2020 Apr 9;11(5):956-962. doi: 10.1021/acsmedchemlett.9b00681. eCollection 2020 May 14. PMID: 32435411.
Evaluation of Varicella Immunity during Pregnancy in Apulia Region, Southern Italy.
Trombetta CM, Montomoli E, Viviani S, Coluccio R, Marchi S. Vaccines (Basel). 2020 May 10;8(2):214. doi: 10.3390/vaccines8020214. PMID: 32397576; PMCID: PMC7348821.
Seroprevalence of antibodies to cytomegalovirus in pregnant women in the Apulia region (Italy).
Trombetta CM, Viviani S, Montomoli E, Marchi S. J Prev Med Hyg. 2021 Jul 30;62(2):E372-E376. doi: 10.15167/2421-4248/jpmh2021.62.2.1800. eCollection 2021 Jun. PMID: 34604575.
Immunogenicity of Calvenza-03 EIV/EHV® Vaccine in Horses: Comparative In Vivo Study.
Pavulraj S, Bergmann T, Trombetta CM, Marchi S, Montomoli E, Alami SSE, Ragni-Alunni R, Osterrieder N, Azab W. Vaccines (Basel). 2021 Feb 17;9(2):166. doi: 10.3390/vaccines9020166. PMID: 33671378.
Maraviroc as a potential HIV-1 latency-reversing agent in cell line models and ex vivo CD4 T cells.
Vicenti I, Dragoni F, Monti M, Trombetta CM, Giannini A, Boccuto A, Saladini F, Rossetti B, De Luca A, Ciabattini A, Pastore G, Medaglini D, Orofino G, Montomoli E, Zazzi M. J Gen Virol. 2021 Jan;102(1). doi: 10.1099/jgv.0.001499. PMID: 33048041.
Development and Assessment of a Pooled Serum as Candidate Standard to Measure Influenza A Virus Group 1 Hemagglutinin Stalk-Reactive Antibodies.
Carreño JM, McDonald JU, Hurst T, Rigsby P, Atkinson E, Charles L, Nachbagauer R, Behzadi MA, Strohmeier S, Coughlan L, Aydillo T, Brandenburg B, García-Sastre A, Kaszas K, Levine MZ, Manenti A, McDermott AB, Montomoli E, Muchene L, Narpala SR, Perera RAPM, Salisch NC, Valkenburg SA, Zhou F, Engelhardt OG, Krammer F. Vaccines (Basel). 2020 Nov 9;8(4):666. doi: 10.3390/vaccines8040666. PMID: 33182279.
Measles Susceptibility in Apulia: The Italian Mirror?
Marchi S, Viviani S, Montomoli E, Trombetta CM. J Infect Dis. 2020 Sep 14;222(8):1414-1415. doi: 10.1093/infdis/jiaa212. PMID: 32343809.
Measles immunity over two decades in two large Italian Regions: How far is the elimination goal?
Marchi S, Remarque EJ, Viviani S, Rizzo C, Monteverde Spencer GT, Coluccio R, Montomoli E, Trombetta CM. Vaccine. 2021 Sep 24;39(40):5928-5933. doi: 10.1016/j.vaccine.2021.08.001. Epub 2021 Aug 26. PMID: 34456073.
Seroprevalence of Hepatitis E Virus in Forestry Workers from Trentino-Alto Adige Region (Northern Italy).
Monini M, Ostanello F, Dominicis A, Tagliapietra V, Vaccari G, Rizzoli A, Trombetta CM, Montomoli E, Di Bartolo I. Pathogens. 2020 Jul 14;9(7):568. doi: 10.3390/pathogens9070568. PMID: 32674277.
Immunogenicity Measures of Influenza Vaccines: A Study of 1164 Registered Clinical Trials.
Domnich A, Manini I, Panatto D, Calabrò GE, Montomoli E. Vaccines (Basel). 2020 Jun 19;8(2):325. doi: 10.3390/vaccines8020325. PMID: 32575440.
The enemy at home: leishmaniasis in the Mediterranean basin, Italy on the focus.
Gianchecchi E, Montomoli E. Expert Rev Anti Infect Ther. 2020 Jun;18(6):563-577. doi: 10.1080/14787210.2020.1751611. Epub 2020 Apr 17. PMID: 32249634.
Exploring the Implication of DDX3X in DENV Infection: gion, Southern Italy.
Trombetta CM, Montomoli E, Viviani S, Coluccio R, Marchi S. Vaccines (Basel). 2020 May 10;8(2):214. doi: 10.3390/vaccines8020214. PMID: 32397576.
Elimination of congenital rubella: a seroprevalence study of pregnant women and women of childbearing age in Italy.
Marchi S, Viviani S, Montomoli E, Trombetta CM. Hum Vaccin Immunother. 2020 Apr 2;16(4):895-898. doi: 10.1080/21645515.2019.1688041. Epub 2019 Nov 26. PMID: 31674859.
Toxoplasma gondii in women of childbearing age and during pregnancy: seroprevalence study in Central and Southern Italy from 2013 to 2017.
Fanigliulo D, Marchi S, Montomoli E, Trombetta CM. Parasite. 2020;27:2. doi: 10.1051/parasite/2019080. Epub 2020 Jan 14. PMID: 31934847.
Immunogenicity and safety of COVID-19 booster vaccination: A population-based clinical trial to identify the best vaccination strategy.
Sieghart D, Hana CA, Dürrschmid C, Heinz LX, Haslacher H, Zlesak M, Piccini G, Manenti A, Montomoli E, Jorda A, Fedrizzi C, Hasenoehrl T, Zdravkovic A, Anderle K, Wiedermann U, Drapalik S, Steinbrecher H, Bergmann F, Firbas C, Jordakieva G, Wagner B, Leonardi M, Pierleoni G, Ballini M, Benincasa L, Marchi S, Trombetta C, Perkmann T, Crevenna R, Zeitlinger M, Bonelli M, Aletaha D, Radner H. J Clin Virol. 2024 Aug;173:105661. doi: 10.1016/j.jcv.2024.105661. Epub 2024 Feb 28. PMID: 38503118.
