SARS-COV-2
Impact of ABO Blood System on Immunogenicity and Vaccine Efficacy of COVID-19 Booster Vaccination—A Population-Based Study of 3066 Individuals.
Sieghart D, Jordakieva G, Dürrschmid C, Hana CA, Tran LV, Heinz LX, Haslacher H, Zlesak M, Marzoner V, Nasztl P, Piccini G, Manenti A, Montomoli E, Jorda A, Fedrizzi C, Hasenoehrl T, Zdravkovic A, Anderle K, Wiedermann U, Drapalik S, Steinbrecher H, Bergmann F, Wagner B, Leonardi M, Pierleoni G, Ballini M, Benincasa L, Marchi S, Trombetta CM, Perkmann T, Crevenna R, Zeitlinger M, Bonelli M, Aletaha D, Radner H. Influenza Other Respir Viruses. 2026;20(8):e70300. doi: 10.1111/irv.70300.
The neutralizing response to SARS-CoV-2 Omicron variants BA.1 and BA.2 in COVID-19 patients and homologous and heterologous vaccinees.
Dapporto F, Leonardi M, Trombetta CM, Semplici C, Piu P, Piccini G, Benincasa L, Marchi S, Andreano E, Lovreglio P, Buonvino N, Decaro N, Stufano A, Lorusso E, Bombardieri E, Ruello A, Viviani S, Rappuoli R, Molesti E, Manenti A, Montomoli E. Hum Vaccin Immunother. 2022 Nov 30;18(6):2129196. doi: 10.1080/21645515.2022.2129196. Epub 2022 Oct 21. PMID: 36269939.
A serological investigation in Southern Italy: was SARS-CoV-2 circulating in late 2019?
Trombetta CM, Marchi S, Viviani S, Manenti A, Casa E, Dapporto F, Remarque EJ, Bollati V, Manini I, Lazzeri G, Montomoli E. Hum Vaccin Immunother. 2022 Nov 30;18(5):2047582. doi: 10.1080/21645515.2022.2047582. Epub 2022 Mar 15. PMID: 35289714.
SARS-CoV-2 Seroconversion and Pregnancy Outcomes in a Population of Pregnant Women Recruited in Milan, Italy, between April 2020 and October 2020.
Accurti V, Gambitta B, Iodice S, Manenti A, Boito S, Dapporto F, Leonardi M, Molesti E, Fabietti I, Montomoli E, Bollati V, Persico N. Int J Environ Res Public Health. 2022 Dec 13;19(24):16720. doi: 10.3390/ijerph192416720. PMID: 36554602.
Evaluation of antibody response to SARS-CoV-2 variants after 2 doses of mRNA COVID-19 vaccine in a correctional facility.
Trombetta CM, Marchi S, Leonardi M, Stufano A, Lorusso E, Montomoli E, Decaro N, Buonvino N, Lovreglio P. Hum Vaccin Immunother. 2022 Dec 30;18(7):2153537. doi: 10.1080/21645515.2022.2153537. Epub 2022 Dec 12. PMID: 36503363.
Surveillance of Severe Acute Respiratory Infection and Influenza Vaccine Effectiveness among Hospitalized Italian Adults, 2021/22 Season.
Panatto D, Domnich A, Chironna M, Loconsole D, Napoli C, Torsello A, Manini I, Montomoli E, Pariani E, Castaldi S, Orsi A, Icardi G; On Behalf Of The It-Bive-Hosp Network Study Group. Vaccines (Basel). 2022 Dec 30;11(1):83. doi: 10.3390/vaccines11010083. PMID: 36679928.
Evaluation of immune response to SARS-CoV-2 Omicron sublineages six months after different vaccination regimens in Italy.
Trombetta CM, Marchi S, Leonardi M, Coppola C, Benincasa L, Marotta MG, Buonvino N, Maes P, Stufano A, Pontrelli D, Vasinioti VI, Manenti A, Camero M, Montomoli E, Decaro N, Lovreglio P. Acta Trop. 2023 Dec;248:107042. doi: 10.1016/j.actatropica.2023.107042. Epub 2023 Oct 18. PMID: 37863379.
Lower frequency of SARS-CoV-2-associated severe respiratory infections among adults vaccinated against the 2021/22 season influenza.
Domnich A, Milano G, Capitani E, Camarri A, Bova G, Capecchi PL, Montomoli E, Manini I. Respir Med Res. 2023 Jun;83:100979. doi: 10.1016/j.resmer.2022.100979. Epub 2022 Nov 25. PMID: 36565562.
A Promising Mechanism Linking SARS-CoV-2 Infection to Adverse Pregnancy Outcomes.
Monti P, Solazzo G, Accurti V, Gambitta B, Iodice S, Boito S, Cantone L, Manenti A, Dioni L, Montomoli E, Persico N, Bollati V. Int J Mol Sci. 2023 May 25;24(11):9278. doi: 10.3390/ijms24119278. PMID: 37298229.
mRNA vaccines and hybrid immunity use different B cell germlines against Omicron BA.4 and BA.5.
Andreano E, Paciello I, Pierleoni G, Maccari G, Antonelli G, Abbiento V, Pileri P, Benincasa L, Giglioli G, Piccini G, De Santi C, Sala C, Medini D, Montomoli E, Maes P, Rappuoli R. Nat Commun. 2023 Mar 28;14(1):1734. doi: 10.1038/s41467-023-37422-y. PMID: 36977711.
SARS-CoV-2 epidemiological trend before vaccination era: a seroprevalence study in Apulia, Southern Italy, in 2020.
Marchi S, Coppola C, Piu P, Benincasa L, Dapporto F, Manenti A, Viviani S, Montomoli E, Trombetta CM. Z Gesundh Wiss. 2023 Feb 4:1-6. doi: 10.1007/s10389-023-01834-3. Online ahead of print. PMID: 36776202.
B cell analyses after SARS-CoV-2 mRNA third vaccination reveals a hybrid immunity like antibody response.
Andreano E, Paciello I, Pierleoni G, Piccini G, Abbiento V, Antonelli G, Pileri P, Manganaro N, Pantano E, Maccari G, Marchese S, Donnici L, Benincasa L, Giglioli G, Leonardi M, De Santi C, Fabbiani M, Rancan I, Tumbarello M, Montagnani F, Sala C, Medini D, De Francesco R, Montomoli E, Rappuoli R. Nat Commun. 2023 Jan 4;14(1):53. doi: 10.1038/s41467-022-35781-6. PMID: 36599850.
In vitro virucidal activity of mouthwashes on SARS-CoV-2.
Buonavoglia A, Lanave G, Marchi S, Lorusso P, Montomoli E, Martella V, Camero M, Prati C, Trombetta CM. Oral Dis. 2022 Nov;28 Suppl 2:2509-2515. doi: 10.1111/odi.14205. Epub 2022 Apr 25. PMID: 35398970.
Durable immunogenicity, adaptation to emerging variants, and low-dose efficacy of an AAV-based COVID-19 vaccine platform in macaques.
Zabaleta N, Bhatt U, Hérate C, Maisonnasse P, Sanmiguel J, Diop C, Castore S, Estelien R, Li D, Dereuddre-Bosquet N, Cavarelli M, Gallouët AS, Pascal Q, Naninck T, Kahlaoui N, Lemaitre J, Relouzat F, Ronzitti G, Thibaut HJ, Montomoli E, Wilson JM, Le Grand R, Vandenberghe LH. Mol Ther. 2022 Sep 7;30(9):2952-2967. doi: 10.1016/j.ymthe.2022.05.007. Epub 2022 May 10. PMID: 35546782.
Immune response to SARS-CoV-2 Omicron variant in patients and vaccinees following homologous and heterologous vaccinations.
Trombetta CM, Piccini G, Pierleoni G, Leonardi M, Dapporto F, Marchi S, Andreano E, Paciello I, Benincasa L, Lovreglio P, Buonvino N, Decaro N, Stufano A, Lorusso E, Bombardieri E, Ruello A, Viviani S, Rappuoli R, Molesti E, Manenti A, Montomoli E. Commun Biol. 2022 Sep 2;5(1):903. doi: 10.1038/s42003-022-03849-0. PMID: 36056181.
Antibody Avidity and Neutralizing Response against SARS-CoV-2 Omicron Variant after Infection or Vaccination.
Dapporto F, Marchi S, Leonardi M, Piu P, Lovreglio P, Decaro N, Buonvino N, Stufano A, Lorusso E, Bombardieri E, Ruello A, Viviani S, Molesti E, Trombetta CM, Manenti A, Montomoli E. J Immunol Res. 2022 Aug 31;2022:4813199. doi: 10.1155/2022/4813199. eCollection 2022. PMID: 36093434.
COVID-19 Outbreak and BNT162b2 mRNA Vaccination Coverage in a Correctional Facility during Circulation of the SARS-CoV-2 Omicron BA.1 Variant in Italy.
Stufano A, Buonvino N, Trombetta CM, Pontrelli D, Marchi S, Lobefaro G, De Benedictis L, Lorusso E, Carofiglio MT, Vasinioti VI, Montomoli E, Decaro N, Lovreglio P. Vaccines (Basel). 2022 Jul 17;10(7):1137. doi: 10.3390/vaccines10071137. PMID: 35891301.
Nasopharyngeal Bacterial Microbiota Composition and SARS-CoV-2 IgG Antibody Maintenance in Asymptomatic/Paucisymptomatic Subjects.
Ferrari L, Favero C, Solazzo G, Mariani J, Luganini A, Ferraroni M, Montomoli E, Milani GP, Bollati V. Front Cell Infect Microbiol. 2022 Jul 6;12:882302. doi: 10.3389/fcimb.2022.882302. eCollection 2022. PMID: 35873175.
SARS-CoV-2 Circulation during the First Year of the Pandemic: A Seroprevalence Study from January to December 2020 in Tuscany, Italy.
Marchi S, Lanave G, Camero M, Dapporto F, Manenti A, Benincasa L, Acciavatti A, Brogi G, Viviani S, Montomoli E, Trombetta CM. Viruses. 2022 Jun 30;14(7):1441. doi: 10.3390/v14071441. PMID: 35891420.
Anatomy of Omicron BA.1 and BA.2 neutralizing antibodies in COVID-19 mRNA vaccinees.
Andreano E, Paciello I, Marchese S, Donnici L, Pierleoni G, Piccini G, Manganaro N, Pantano E, Abbiento V, Pileri P, Benincasa L, Giglioli G, Leonardi M, Maes P, De Santi C, Sala C, Montomoli E, De Francesco R, Rappuoli R. Nat Commun. 2022 Jun 13;13(1):3375. doi: 10.1038/s41467-022-31115-8. PMID: 35697673.
Structural insights of a highly potent pan-neutralizing SARS-CoV-2 human monoclonal antibody.
Torres JL, Ozorowski G, Andreano E, Liu H, Copps J, Piccini G, Donnici L, Conti M, Planchais C, Planas D, Manganaro N, Pantano E, Paciello I, Pileri P, Bruel T, Montomoli E, Mouquet H, Schwartz O, Sala C, De Francesco R, Wilson IA, Rappuoli R, Ward AB. Proc Natl Acad Sci U S A. 2022 May 17;119(20):e2120976119. doi: 10.1073/pnas.2120976119. Epub 2022 May 12. PMID: 35549549.
Safety and serum distribution of anti-SARS-CoV-2 monoclonal antibody MAD0004J08 after intramuscular injection.
Lanini S, Milleri S, Andreano E, Nosari S, Paciello I, Piccini G, Gentili A, Phogat A, Hyseni I, Leonardi M, Torelli A, Montomoli E, Paolini A, Frosini A, Antinori A, Nicastri E, Girardi E, Plazzi MM, Ippolito G, Vaia F, Della Cioppa G, Rappuoli R. Nat Commun. 2022 Apr 27;13(1):2263. doi: 10.1038/s41467-022-29909-x. PMID: 35477725.
Cellular and Humoral Immune Responses and Breakthrough Infections After Two Doses of BNT162b Vaccine in Healthcare Workers (HW) 180 Days After the Second Vaccine Dose.
Mangia A, Serra N, Cocomazzi G, Giambra V, Antinucci S, Maiorana A, Giuliani F, Montomoli E, Cantaloni P, Manenti A, Piazzolla V. Front Public Health. 2022 Mar 31;10:847384. doi: 10.3389/fpubh.2022.847384. eCollection 2022. PMID: 35433614.
Yellow Fever: Origin, Epidemiology, Preventive Strategies and Future Prospects.
Gianchecchi E, Cianchi V, Torelli A, Montomoli E. Vaccines (Basel). 2022 Feb 27;10(3):372. doi: 10.3390/vaccines10030372. PMID: 35335004.
Evaluation and correlation between SARS-CoV-2 neutralizing and binding antibodies in convalescent and vaccinated subjects.
Manenti A, Gianchecchi E, Dapporto F, Leonardi M, Cantaloni P, Fattorini F, Piu P, Bollati V, Pastorino U, Apolone G, Sozzi G, Montomoli E. J Immunol Methods. 2022 Jan;500:113197. doi: 10.1016/j.jim.2021.113197. Epub 2021 Nov 26. PMID: 34843712.
Timeline of SARS-CoV-2 Spread in Italy: Results from an Independent Serological Retesting.
Montomoli E, Apolone G, Manenti A, Boeri M, Suatoni P, Sabia F, Marchianò A, Bollati V, Pastorino U, Sozzi G. Viruses. 2021 Dec 30;14(1):61. doi: 10.3390/v14010061. PMID: 35062265.
Hybrid immunity improves B cells and antibodies against SARS-CoV-2 variants.
Andreano E, Paciello I, Piccini G, Manganaro N, Pileri P, Hyseni I, Leonardi M, Pantano E, Abbiento V, Benincasa L, Giglioli G, De Santi C, Fabbiani M, Rancan I, Tumbarello M, Montagnani F, Sala C, Montomoli E, Rappuoli R. Nature. 2021 Dec;600(7889):530-535. doi: 10.1038/s41586-021-04117-7. Epub 2021 Oct 20. PMID: 34670266.
Antibodies specific to SARS-CoV-2 proteins N, S and E in COVID-19 patients in the normal population and in historical samples.
Szymczak A, Jędruchniewicz N, Torelli A, Kaczmarzyk-Radka A, Coluccio R, Kłak M, Konieczny A, Ferenc S, Witkiewicz W, Montomoli E, Miernikiewicz P, Bąchor R, Dąbrowska K. J Gen Virol. 2021 Nov;102(11):001692. doi: 10.1099/jgv.0.001692. PMID: 34816794.
The theory and practice of the viral dose in neutralization assay: Insights on SARS-CoV-2 “doublethink” effect.
Manenti A, Molesti E, Maggetti M, Torelli A, Lapini G, Montomoli E. J Virol Methods. 2021 Nov;297:114261. doi: 10.1016/j.jviromet.2021.114261. Epub 2021 Aug 14. PMID: 34403775.
Reply to comments on: Unexpected detection of SARS-CoV-2 antibodies in the prepandemic period in Italy.
Sozzi G, Manenti A, Boeri M, Sabia F, Montomoli E, Pastorino U, Apolone G. Tumori. 2021 Oct;107(5):472-473. doi: 10.1177/03008916211009688. Epub 2021 Apr 20. PMID: 33877026.
Unexpected detection of SARS-CoV-2 antibodies in the prepandemic period in Italy.
Apolone G, Montomoli E, Manenti A, Boeri M, Sabia F, Hyseni I, Mazzini L, Martinuzzi D, Cantone L, Milanese G, Sestini S, Suatoni P, Marchianò A, Bollati V, Sozzi G, Pastorino U. Tumori. 2021 Oct;107(5):446-451. doi: 10.1177/0300891620974755. Epub 2020 Nov 11. PMID: 33176598.
Epidemiological and virological surveillance of Severe Acute Respiratory Infections in the 2019/2020 season in Siena, Tuscany, Italy.
Capitani E, Montomoli E, Camarri A, Bova G, Capecchi PL, Mercone A, Nante N, Manini I. J Prev Med Hyg. 2021 Sep 15;62(3):E782-E788. doi: 10.15167/2421-4248/jpmh2021.62.3.2297. eCollection 2021 Sep. PMID: 34909509.
SARS-CoV-2 escape from a highly neutralizing COVID-19 convalescent plasma.
Andreano E, Piccini G, Licastro D, Casalino L, Johnson NV, Paciello I, Dal Monego S, Pantano E, Manganaro N, Manenti A, Manna R, Casa E, Hyseni I, Benincasa L, Montomoli E, Amaro RE, McLellan JS, Rappuoli R. Proc Natl Acad Sci U S A. 2021 Sep 7;118(36):e2103154118. doi: 10.1073/pnas.2103154118. PMID: 34417349.
Evaluation of the automated LIAISON® SARS-CoV-2 Trimeric S IgG assay for the detection of circulating antibodies.
Bonelli F, Blocki FA, Bunnell T, Chu E, De La O A, Grenache DG, Marzucchi G, Montomoli E, Okoye L, Pallavicini L, Streva VA, Torelli A, Wagner A, Zanin D, Zierold C, Wassenberg JJ. Clin Chem Lab Med. 2021 Mar 15;59(8):1463-1467. doi: 10.1515/cclm-2021-0023. Print 2021 Jul 27. PMID: 33711225.
Serum Neutralizing Activity against B.1.1.7, B.1.351, and P.1 SARS-CoV-2 Variants of Concern in Hospitalized COVID-19 Patients.
Trombetta CM, Marchi S, Viviani S, Manenti A, Benincasa L, Ruello A, Bombardieri E, Vicenti I, Zazzi M, Montomoli E. Viruses. 2021 Jul 12;13(7):1347. doi: 10.3390/v13071347. PMID: 34372553.
Comparative analyses of SARS-CoV-2 binding (IgG, IgM, IgA) and neutralizing antibodies from human serum samples.
Mazzini L, Martinuzzi D, Hyseni I, Benincasa L, Molesti E, Casa E, Lapini G, Piu P, Trombetta CM, Marchi S, Razzano I, Manenti A, Montomoli E. J Immunol Methods. 2021 Feb;489:112937. doi: 10.1016/j.jim.2020.112937. Epub 2020 Nov 28. PMID: 33253698.
SARS-CoV-2 escape in vitro from a highly neutralizing COVID-19 convalescent plasma.
Andreano E, Piccini G, Licastro D, Casalino L, Johnson NV, Paciello I, Dal Monego S, Pantano E, Manganaro N, Manenti A, Manna R, Casa E, Hyseni I, Benincasa L, Montomoli E, Amaro RE, McLellan JS, Rappuoli R. bioRxiv. 2020 Dec 28:2020.12.28.424451. doi: 10.1101/2020.12.28.424451. Preprint. PMID: 33398278.
Serological follow-up of SARS-CoV-2 asymptomatic subjects.
Milani GP, Dioni L, Favero C, Cantone L, Macchi C, Delbue S, Bonzini M, Montomoli E, Bollati V; UNICORN Consortium. Sci Rep. 2020 Nov 18;10(1):20048. doi: 10.1038/s41598-020-77125-8. PMID: 33208819.
A review of COVID-19 vaccines in development: 6 months into the pandemic.
Sanicas M, Sanicas M, Diop D, Montomoli E. Pan Afr Med J. 2020 Oct 5;37:124. doi: 10.11604/pamj.2020.37.124.24973. eCollection 2020. PMID: 33425157.
Evaluation of SARS-CoV-2 neutralizing antibodies using a CPE-based colorimetric live virus micro-neutralization assay in human serum samples.
Manenti A, Maggetti M, Casa E, Martinuzzi D, Torelli A, Trombetta CM, Marchi S, Montomoli E. J Med Virol. 2020 Oct;92(10):2096-2104. doi: 10.1002/jmv.25986. Epub 2020 May 17. PMID: 32383254.
Characterisation of SARS-CoV-2 Lentiviral Pseudotypes and Correlation between Pseudotype-Based Neutralisation Assays and Live Virus-Based Micro Neutralisation Assays.
Hyseni I, Molesti E, Benincasa L, Piu P, Casa E, Temperton NJ, Manenti A, Montomoli E. Viruses. 2020 Sep 10;12(9):1011. doi: 10.3390/v12091011. PMID: 32927639.
SARS-CoV-2 infection among asymptomatic homebound subjects in Milan, Italy.
Milani GP, Montomoli E; UNICORN Consortium investigators, Bollati V, Albetti B, Bandi C, Bellini T, Bonzini M, Buscaglia M, Cantarella C, Cantone L, Carugno M, Casartelli S, Cavaletti G, D’Alessandro S, De Chiara F, Delbue S, Dioni L, Eberini I, Favero C, Ferrari L, Ferraroni M, Galastri L, Galli C, Hoxha M, Iodice S, La Vecchia C, Macchi C, Manini I, Marchi S, Mariani J, Pariani E, Pesatori AC, Rota F, Ruscica M, Schioppo T, Tarantini L, Trombetta CM, Valsecchi MG, Vicenzi M, Zanchetta G. Eur J Intern Med. 2020 Aug;78:161-163. doi: 10.1016/j.ejim.2020.06.010. Epub 2020 Jun 9. PMID: 32564906.
Moderate Vaccine Effectiveness against Severe Acute Respiratory Infection Caused by A(H1N1)pdm09 Influenza Virus and No Effectiveness against A(H3N2) Influenza Virus in the 2018/2019 Season in Italy.
Rizzo C, Gesualdo F, Loconsole D, Pandolfi E, Bella A, Orsi A, Guarona G, Panatto D, Icardi G, Napoli C, Orsi GB, Manini I, Montomoli E, Campagna I, Russo L, Alfonsi V, Puzelli S, Reale A, Raucci U, Piccioni L, Concato C, Ciofi Degli Atti ML, Villani A, Chironna M, Tozzi AE. Vaccines (Basel). 2020 Jul 30;8(3):427. doi: 10.3390/vaccines8030427. PMID: 32751584.
Characterization of antibody response in asymptomatic and symptomatic SARS-CoV-2 infection.
Marchi S, Viviani S, Remarque EJ, Ruello A, Bombardieri E, Bollati V, Milani GP, Manenti A, Lapini G, Rebuffat A, Montomoli E, Trombetta CM. PLoS One. 2021 Jul 2;16(7):e0253977. doi: 10.1371/journal.pone.0253977. eCollection 2021. PMID: 34214116.
Extremely potent human monoclonal antibodies from COVID-19 convalescent patients.
Andreano E, Nicastri E, Paciello I, Pileri P, Manganaro N, Piccini G, Manenti A, Pantano E, Kabanova A, Troisi M, Vacca F, Cardamone D, De Santi C, Torres JL, Ozorowski G, Benincasa L, Jang H, Di Genova C, Depau L, Brunetti J, Agrati C, Capobianchi MR, Castilletti C, Emiliozzi A, Fabbiani M, Montagnani F, Bracci L, Sautto G, Ross TM, Montomoli E, Temperton N, Ward AB, Sala C, Ippolito G, Rappuoli R. Cell. 2021 Apr 1;184(7):1821-1835.e16. doi: 10.1016/j.cell.2021.02.035. Epub 2021 Feb 23. PMID: 33667349.
Detection of IgM, IgG and SARS-CoV-2 RNA among the personnel of the University of Milan, March through May 2020: the UNICORN study.
Milani GP, Rota F, Favero C, Dioni L, Manenti A, Hoxha M, Pariani E, Albetti B, Pesatori AC, Montomoli E, Bollati V. BMJ Open. 2021 Mar 24;11(3):e046800. doi: 10.1136/bmjopen-2020-046800. PMID: 33762247.
